2021 Archive

three people at a table, two sitting and one standing
three people at a table, two sitting and one standing
Clinical

Leveraging machine learning sparks innovation in bone marrow transplantation

Alex Generous, PhD

Machine learning and bone marrow transplantation combine to improve survival predictions.

Graphic depicting infant vaccination
Graphic depicting infant vaccination
Research

Exploring the interplay between vaccines and immune system development in infants

Brian O'Flynn, PhD

Explore new research delving into pediatric immune responses to vaccination

Graphic depicting two hands and a globe
Graphic depicting two hands and a globe
Outreach

St. Jude Global builds pathology and laboratory medicine capacity and community

Alex Generous, PhD

The St. Jude Global Pathology and Laboratory Medicine Transversal aims to improve diagnostic testing worldwide.

Francesca Ferrara, PhD
Francesca Ferrara, PhD
Clinical

Shared Resource Spotlight: St. Jude Vector Laboratory (SJVL)

Emilia Asante, PhD

The St. Jude Vector Laboratory advances gene therapy through viral vectors, advancing scientific and therapeutic innovation.

Nickhill Bhakta and Nancy Bolous
Nickhill Bhakta and Nancy Bolous
Outreach

Bridging the pediatric cancer budgeting gap in national cancer control plans

Alex Generous, PhD

A new rapid budgeting tool increases the likelihood pediatric cancer will be included in national cancer control plans globally.

Investigator Insights

5 Questions for Laura Jolovic

Erin Podolak, MA and Laura Jolovic

Meet St. Jude radiation therapist Laura Jolovic and learn how she provides care for children with cancer as well as mentors students interested in a career in pediatric radiation oncology.

3 men in a lab
3 men in a lab
Research

CRISPR kickstarts combination drug discovery for neuroblastoma

Alex Generous, PhD

A CRISPR screen reveals a potential combination therapy for relapsed neuroblastoma.

Outreach

Building blocks: St. Jude Global guides reestablishment of health care capacity during crisis

Erin Podolak, MA

St. Jude Global helps provide a framework for rebuilding health care capacity after a crisis.

Research

Finding the big-TIME players holding back CAR T–cell therapy for high-grade gliomas

Alex Generous, PhD

Explore how tumor-associated macrophages shape CAR T-cell therapy efficacy in high-grade gliomas.

Alaa Refaat, PhD
Alaa Refaat, PhD
Investigator Insights

5 Questions for Alaa Refaat

Erin Podolak, MA and Alaa Refaat, PhD

Meet St. Jude senior scientist Alaa Refaat, PhD, and learn about his work to develop treatments for childhood brain tumors using chemical biology approaches.

Jasmine Turner analyzes data from samples to determine the presence of influenza. She credits her mother for encouragement and inspiration to pursue a scientific career.
Jasmine Turner analyzes data from samples to determine the presence of influenza. She credits her mother for encouragement and inspiration to pursue a scientific career.
Investigator Insights

Jasmine Turner: Overcoming obstacles, rising to meet challenges

Mike O’Kelly

For Jasmine Turner, resilience and tenacity were required to enter a field with very few Black women. There weren’t many women or teachers of color in her scientific courses—no one with similar experiences to help guide her or focus her talents. She turned to her mother for encouragement and inspiration.

Different types of pediatric cancer treatments are ototoxic, or damaging to the ears. As cancer treatments become more effective and survival rates increase, we’re getting a better picture of how various treatments affect patients later on.
Different types of pediatric cancer treatments are ototoxic, or damaging to the ears. As cancer treatments become more effective and survival rates increase, we’re getting a better picture of how various treatments affect patients later on.
Clinical

What we’ve found out about hearing loss and cognitive function in children

Johnnie Bass, AuD, PhD

This study, to our knowledge, is the first to objectively measure hearing and neurocognitive function in a large cohort of long-term survivors of childhood cancer stratified by treatment exposures.

Andrea Stubbs points to finding her niche while working to address youth HIV acquisition and transmission, and plans to use those same skills to increase HPV vaccinations.
Andrea Stubbs points to finding her niche while working to address youth HIV acquisition and transmission, and plans to use those same skills to increase HPV vaccinations.
Investigator Insights

Making purposeful connections to help others grow and develop

Chris Pennington

Andrea Stubbs shares her experiences that shaped her career in community outreach to raise awareness for both HIV and HPV.

Pat Keel credits a previous job where she stepped out of her comfort zone to grow professionally and build unity within teams working toward a common goal. Photo from early 2020.
Pat Keel credits a previous job where she stepped out of her comfort zone to grow professionally and build unity within teams working toward a common goal. Photo from early 2020.
Investigator Insights

Leadership begins where the comfort zone ends

St. Jude Progress

Women of St. Jude highlights the influences and events that shaped the career of Pat Keel, who shares lessons she’s learned about teamwork and leadership.

Quality sickle cell disease treatment shouldn’t depend upon where you live
Quality sickle cell disease treatment shouldn’t depend upon where you live
Clinical

The global burden of sickle cell disease: The quality of treatment shouldn’t depend upon where you live

Ayobami Olanrewaju, MD

Survival and quality of life for many with sickle cell disease depends upon where they live. Here’s what a doctor wants to do to fix that.

How do fathers grieve the loss of a child?
How do fathers grieve the loss of a child?
Clinical

How do fathers grieve the loss of a child?

Michael J. McNeil, MD

Fathers express grief through keeping busy or focusing on work – different than a mother’s grief. But fathers may not be getting the support they need after the loss of a child.

A career of service to those in need
A career of service to those in need
Investigator Insights

A career of service to those in need

Katy Hobgood

Nehali Patel, MD, grew up helping those in need. Read how working with HIV-infected children has shaped her medical career.

The path to cancer prevention Includes HPV vaccination
The path to cancer prevention Includes HPV vaccination
Outreach

The path to cancer prevention includes HPV vaccination

Heather Brandt, PhD

There’s a global push to increase HPV vaccination rates, and if successful, there are these future benefits everyone can enjoy.

A blend of art and math inspires Hankins’ science
A blend of art and math inspires Hankins’ science
Investigator Insights

A blend of art and math inspires Hankins’ science

Elizabeth Whittington

St. Jude highlights Jane Hankins, who offers insights into how the artistic side of medicine shaped her education to become a hematologist.

Blocking the progression of pre-leukemic disorders
Blocking the progression of pre-leukemic disorders
Research

Blocking the progression of pre-leukemic disorders

Erin Podolak, MA

Genetic changes in the biology of blood cells can lead them down a path to cancer. This researcher is figuring out how that happens.