Optimizing leukemia treatment through pharmaceutical science
Limiting allergic reactions, optimizing treatments and reducing unwanted late effects is part of the pharmaceutical research being conduction to better cancer treatment.
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Category: Research
Discovering how T cell “exhaustion” is triggered could energize cancer immunotherapy
Researchers discovered a gene that triggers T cell exhaustion, limiting the body’s ability to fight disease. Now learning how to inhibit that gene may lead to improved cancer and viral infections.
Read MoreEnzymes that unlock stress granules, our cells’ biological ‘storm shelters,’ open pathway to treating muscle, brain disorders
Cellular enzymes that unlock biological “storm shelters” open pathway to treating muscle and brain disorders.
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Length matters in dipeptide repeat polypeptides – and can be a way to treat ALS
When this gene mutates, it causes a series of toxic cellular events that can be an indicator for ALS. Research through a revolutionary machine has identified the processes involved when this mutation happens.
Read MoreHaving trouble reading? Hearing loss could be part of the problem
Hearing loss is a common side effect of brain tumors and their treatment. We’ve found a link between hearing loss and difficulty with reading.
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Researchers introduce real-time clinical genomics data using St. Jude Cloud platform at 2019 ASCO annual meeting
Scott Newman, PhD, shares the release of real-time clinical genomics data through the St. Jude Cloud platform at the 2019 American Society of Clinical Oncology (ASCO) meeting in Chicago, Illinois.
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Researchers develop method to dramatically reduce error rate in next-generation sequencing
This new software shrinks the error rate in next-generation sequencing data as much as 100-fold, which would likely speed early detection of relapse and other threats.
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Genetic variations in a fourth gene linked to elevated leukemia risk in Hispanic children
Genome wide association studies reveal fourth gene that links increased risk of leukemia with Hispanic children.
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Pediatric melanoma mystery solved by genome sequencing research
Getting the complete genomic data from a common case of skin cancer revealed a new genetic driver in children and adults.
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From evolutionary biology to immunology via bioinformatics
Talent Talks career profile: bioinformatics research scientist Jeremy Chase Crawford, PhD, combines his graduate training in biology with resourceful computing to devise new methods for generating data previously inaccessible to St. Jude immunologists.
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Researchers identify new molecular triggers for cell’s ‘executioner’
New molecular control signals for cell killing processes identified, opens possibly pathways for treatment of cancers and other disorders.
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What hidden hazards lie beneath the surface of genome editing?
Read how this researcher is uncovering the hidden dangers of gene editing.
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