Category: Research
Five years later: gene therapy for ‘bubble boy’ disease
| May 19, 2022Interim results point to enduring immune function following gene therapy for Infants with ‘bubble boy’ disease
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Metabolic processes may yield a new therapeutic window for hard-to-treat brain tumors
| Apr 22, 2022In his laboratory at St. Jude, Stephen Mack, PhD, is researching how metabolic and epigenetic pathways might be perturbed to help treat DIPG, a lethal childhood brain tumor.
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The double-edged sword of being both parent and blood stem cell donor
| Mar 8, 2022What are the potential psychological and emotional risks and rewards for parents who serve as their children’s bone marrow donors?
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CoNGA: Deciphering the dance of T-cell differentiation
| Aug 23, 2021St. Jude scientists have created an algorithm to help group T-cells by their function by evaluating two different types of data, T-cell receptor sequences and gene expression.
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St. Jude biostatisticians create a novel clinical trial design software
| Jul 27, 2021Description: St. Jude biostatisticians have developed a new method for designing phase 2 clinical trials with a small sample size. The approach uses a mathematical model called Bayesian probability . The researchers created free software to implement the process.
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For the growing number of childhood cancer survivors, five-year survival is just the beginning
| May 11, 2021As cancer survivorship changes, new benchmarks must be set to redefine survivorship research and treatment success.
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Immune markers offer clues to antibody production in response to flu
| Apr 7, 2021Scientists are learning more about antibody production in response to flu, including how they develop from helper T cells and monocytes.
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What we’ve found out about hearing loss and cognitive function in children
| Mar 25, 2021This study, to our knowledge, is the first to objectively measure hearing and neurocognitive function in a large cohort of long-term survivors of childhood cancer stratified by treatment exposures.
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How do fathers grieve the loss of a child?
| Mar 10, 2021Fathers express grief through keeping busy or focusing on work – different than a mother’s grief. But fathers may not be getting the support they need after the loss of a child.
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Blocking the progression of pre-leukemic disorders
| Feb 25, 2021Genetic changes in the biology of blood cells can lead them down a path to cancer. This researcher is figuring out how that happens.
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